What Happens to Your Body When You Take Mushroom Supplements

Estimated read time 5 min read



Recently, mushroom supplements have soared in popularity. These supplements, derived from species like Reishi, Maitake and Lion’s Mane, are celebrated for their purported health benefits. Now, people are turning to them for a multitude of reasons, from enhancing immune health to reducing stress to better mental clarity and focus.

If you’re wondering what happens to your body when you take mushroom supplements and whether they’re safe, we have answers. So, if you could use a bit of fungal magic, read on to discover what these supplements can do for you.

What Are Mushroom Supplements? 

Mushroom supplements are concentrated versions of various types of medicinal mushrooms. However, these aren’t the mushrooms you’ll normally find at your grocery store. Typically available in powder, capsule and tincture form, these supplements are derived from species like Reishi, Maitake and Lion’s Mane. And each brings its unique array of benefits to the table.

Potential Mushroom Supplements Benefits

The health benefits of mushroom supplements depend on the variety and dose you take. Here’s what they might do for your health.

May Help You Manage Stress

Reishi mushroom has been a cornerstone of traditional medicine for centuries, particularly in Asian cultures. Its primary health benefit is its profound ability to reduce stress and promote a sense of calm. Reishi boasts adaptogenic properties, which enable the body to better cope with and adapt to various stressors. The active compounds in Reishi, such as triterpenoids and polysaccharides, help modulate the body’s stress response by regulating the production of the stress hormone cortisol.,

Might Support Your Immune Health

If you are taking a mushroom supplement that contains maitake mushrooms, you may be in luck during cold and flu season. How so? Maitake mushrooms (also known as “Hen of the Woods”) are rich in unique immune-supporting fibers called beta-glucans. In the body, beta-glucans enhance the function of various immune cells that combat illness by defending against pathogens and infections.

May Improve Brain Function and Mental Focus

Taking a mushroom supplement that contains Lion’s Mane may support cognitive health and help you focus more clearly. Lion’s Mane contains brain-enhancing bioactive compounds such as hericenones and erinacines. These have been shown to stimulate the production of nerve growth factor (NGF), which is crucial for brain cell growth, maintenance and survival. Because NGF is also essential for learning and memory, a Lion’s Mane supplement may help you focus better.

Potential Risks/Precautions

While mushroom supplements offer numerous potential health benefits, it is essential to be aware of possible risks. First and foremost, individuals with allergies to fungi should exercise caution, as these supplements may trigger allergic reactions, including skin rashes, itching or respiratory issues. Additionally, those who are pregnant, nursing, or have pre-existing medical conditions should consult with a healthcare provider before starting any new supplement to avoid adverse effects.

As helpful as these supplements may be for adults, they’re not appropriate for children. “I generally do not recommend mushroom supplements for children under seven, as their immune systems are still developing and functional mushrooms interact with immune function,” says Danielle Ryan Dawson, RH, a registered herbalist and head of education and innovation at Four Sigmatic. She also notes that Reishi mushroom may lower blood pressure and should be avoided when taking blood pressure medication. 

It is also crucial to source mushroom supplements from reputable manufacturers to ensure quality and safety. Some products may contain contaminants or may not meet the claimed potency, leading to ineffective or potentially harmful results. Following the recommended dosage is critical, too, as overconsumption of mushroom supplements can lead to digestive issues such as nausea, diarrhea or upset stomach. 

What to Look for in a Mushroom Supplement

When choosing a mushroom supplement, look for one that is free of fillers, additives or unnecessary binders. These can dilute the supplement’s effectiveness and potentially cause unwanted side effects.

You’ll also want to look for supplements that are certified USDA organic and are third-party lab-tested by an organization such as NSF. “Mushrooms are bioaccumulators, meaning they have a greater ability to absorb what they grow on,” says Dawson. “This means they can pick up and accumulate things like heavy metals from the substrate.” 

Frequently Asked Questions


  • What does a mushroom supplement do for you?

    Mushroom supplements contain bioactive substances that are believed to offer a range of health benefits, including stress relief and better immune health, cognitive function and mental clarity.


  • How long does it take for mushroom supplements to work?

    The effects of mushroom supplements can vary depending on the individual and the specific type of mushroom. 


  • Is it safe to take mushroom supplements every day?

    For most people, taking mushroom supplements daily is considered safe when consumed in recommended dosages. However, it is essential to follow the manufacturer’s guidelines and consult with your healthcare provider if you have an underlying health condition.


  • Are mushroom supplements safe for everyone?

    Mushroom supplements are safe for many, but not all, people. Individuals with certain health conditions, such as autoimmune diseases or mushroom allergies, should exercise caution. Pregnant or breastfeeding women and people on immunosuppressive medications should consult their healthcare provider before using mushroom supplements. 

The Bottom Line

Mushroom supplements can be a beneficial addition to your wellness routine, offering a variety of health advantages such as stress relief and enhanced immune function, cognitive performance and mental clarity. However, it is crucial to use them responsibly and adhere to recommended dosages. Of course, it’s always a good idea to speak with your healthcare provider before starting any new supplement, especially if you’re living with an underlying health condition. While not everyone may experience the same benefits, incorporating mushroom supplements into a balanced and healthy lifestyle can be a natural way for many people to enhance their wellbeing.



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