The 5 Best Drinks if You’re Taking Weight Loss Medications

It’s no secret that what you eat plays a crucial role when trying to lose weight. But did you know your choice of drinks can impact your weight management efforts when taking weight loss medications? Certain beverages can complement the effects of weight loss medications, support hydration and provide essential nutrients, while others may lead to unwanted side effects or make it harder to lose weight.

Weight loss medications are prescription drugs designed to support weight loss efforts by reducing appetite, slowing digestion or helping regulate blood sugar levels. They’re typically recommended for people who struggle to lose weight through diet and lifestyle changes alone or for those managing a health conditions like diabetes or high blood pressure where weight loss may help improve the condition. “Some weight loss drugs, like GLP-1 medications, directly reduce blood sugar, which can help people manage both diabetes and weight at the same time. This can make it easier to follow a lower-calorie diet and help you stick to it long-term,” explains Melissa Mitri, M.S., RD, nutrition writer and owner of Melissa Mitri Nutrition.

Here, we’ll outline the best drinks to consume if you’re taking weight loss medications to help you feel your best and stay on track with your weight loss goals.

1. Water

“Water is one of the healthiest beverages, especially when taking weight loss medications,” says Mitri. “It’s calorie-free and one of the most hydrating beverages available. Staying hydrated promotes digestion, helps manage blood sugar levels and keeps the body functioning at its best.”

Drinking water throughout the day can help prevent dehydration, support healthy metabolism and increase satiety, helping reduce overall calorie intake.

Hydration needs vary based on individual factors, but most people should aim for at least eight 8-ounce glasses of water daily, adjusted according to your needs. Try adding lemon, cucumber slices or fresh mint for extra flavor without the extra calories or added sugar, like our Lemon, Cucumber & Mint Infused Water.

2. Seltzer

If water is too plain for you, seltzer offers a bubbly, refreshing option that’s just as hydrating. “Seltzer can be a nice alternative to water, especially if you enjoy carbonation. It’s calorie-free and can add variety to your hydration routine,” explains Mitri. Seltzer can also help with mild nausea or indigestion—two common side effects of weight loss medications.

Look for plain or naturally-flavored seltzers that are free of added sugars or artificial sweeteners, like this Raspberry Ginger Lime Seltzer.

3. Green Tea

Some older research suggests that green tea is a fantastic drink choice for those on weight loss medications since it has antioxidant properties and some metabolism-supporting benefits. “Green tea has minimal calories, is hydrating and contains an antioxidant called EGCG, which can support fat burning and metabolism,” says Mitri. “It may also modestly increase daily calorie burn by up to 4%.”

Brew green tea at home to control the amount of added sugar it contains, or choose an unsweetened bottled version. Enjoy it hot or cold, like our Warm Honey Green Tea or Green Jasmine-Mint Iced Tea with Lemon.

4. Black Coffee

If you’re a coffee drinker, consuming it black may be an energy-boosting and low-calorie choice that supports metabolism. “Black coffee is essentially calorie-free and may support a healthy metabolism, especially if you drink it without added sugar or cream,” explains Mitri. 

While caffeine has a mild diuretic effect, a 2014 study found that moderate consumption does not impact hydration levels. Other more recent research suggests caffeine may help boost fat-burning during exercise.

Stick to drinking coffee black to keep it low-calorie. Minimize adding sugar, cream or flavored syrups, as they can quickly add up and potentially interfere with your weight loss goals. Curious how to brew a healthy cup of coffee? Check out these 9 Rules for How to Make a Perfect Cup.

5. Protein Shakes

“Protein shakes can be a beneficial beverage when taking weight loss medications, providing hydration and a way to add in some extra protein,” Mitri explains. “Since these medications can reduce appetite, it can sometimes be difficult to meet your daily nutrient goals for protein, vitamins and minerals. Incorporating a premade protein shake that is low in added sugar can serve as a nutritious snack to hydrate and nourish you at the same time. When choosing a protein shake, look for one with at least 20 grams of protein to support weight loss and muscle health.”

According to a 2021 study in Clinical Nutrition, whey protein powder is a lower-cost and easy-to-find supplement that can be a helpful addition to your weight loss plan.

Need some ideas for incorporating protein powder into your diet? Try our Chocolate-Peanut Butter Protein Shake or Almond Butter & Banana Protein Smoothie.

The Bottom Line

If you’re taking weight loss medications, staying hydrated and choosing drinks that support your medication’s effects can significantly impact your results and overall well-being. Water is the top expert-recommended choice to stay hydrated, while seltzer, green tea, black coffee and protein shakes can also help support hydration, metabolism and nutrient intake. As always, speak with a healthcare provider or registered dietitian for any questions or concerns regarding weight loss medications.